How would doctors and scientists respond today if a mysterious disease started to spread through a major American city?

Do you think it was fair of the town of Pembroke to prevent fever victims from escaping Philadelphia? Why or why not?

Research the work of Dr. Walter Reed. How do mosquitoes spread yellow fever? What other diseases do mosquitoes spread?

Mattie's grandfather didn't think there was any need to leave when the fever started to spread. Why did some people stay? Would you have stayed?

Make a list of words they used in 1793 that we don't use today. What words do we use today might sound strange in the year 2200?

What was Philadelphia like in 1793? What were the advantages and disadvantages of living in the countryside outside of Philadelphia?